Anti-Huamn sphingosine 1-phosphate receptor 1 (S1PR1) Mouse Monoclonal Antibody (DBOA10006), 100 ug DBOA10006

Anti-Huamn sphingosine 1-phosphate receptor 1 (S1PR1) Mouse Monoclonal Antibody (DBOA10006), 100 ug Signal Transduction DBio DBOA10006
Supplier: DBio
Product Code: DBOA10006
Availability: In Stock

Anti-Huamn sphingosine 1-phosphate receptor 1 (S1PR1) Mouse Monoclonal Antibody (DBOA10006), 100 ugy 

Any application comments (selling point?)

S1PR1 Antibody images

Western Blotting  and IHC image

anti-S1PR1 IHC image

Background

Sphingosine-1-phosphate receptor 1 (S1P receptor 1 or S1P1), also known as endothelial differentiation gene 1 (EDG1) is a protein that in humans is encoded by the S1PR1 gene. S1PR1 is a G-protein-coupled receptor which binds the bioactive signaling molecule sphingosine 1-phosphate (S1P). S1PR1 belongs to a sphingosine-1-phosphate receptor subfamily comprising five members (S1PR1-5).[1] S1PR1 was originally identified as an abundant transcript in endothelial cells[2] and it has an important role in regulating endothelial cell cytoskeletal structure, migration, capillary-like network formation and vascular maturation.[3][4] In addition, S1PR1 signaling is important in the regulation of lymphocyte maturation, migration and trafficking.[5][6]

Product datasheet:

Overview

 

Product Name  

Anti-Huamn sphingosine 1-phosphate receptor 1 (S1PR1) Mouse Monoclonal Antibody (DBOA10006), 100 ug

Description

Anti-Huamn sphingosine 1-phosphate receptor 1 (S1PR1) Mouse Monoclonal Antibody (DBOA10006), 100 ug, can be used in studying S1PR1 protein expression in cultured cells or tissue samples.

Tested Applications

WB, IHC

Species Reactivities

Reacts with: c-myc tag

Immunogen     

c-myc tag peptide

Positive Control

N/A

 

Properties

 

Form 

Freeze dried solid

Storage Instructions

Store at +4°C long term.  After reconstitution, Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

Storage Buffer              

When reconstituted with 100 deionized water, PBS with no preservatives.

Constituent

PBS

Purity  

Purified by protein A

Clonality

Monoclonal

Clone Name

P1S

Isotype

IgG

Applications

The application notes include recommended starting dilutions; optimal dilutions or concentrations should be determined by the end user.

WB

1/500 - 1/2000.

IHC

1/200 - 1/1000

 

General
Gene Symbol S1PR1 ; CD363; CHEDG1; D1S3362; ECGF1; EDG-1; EDG1; S1P1
Applications WB, IF, IHC, IP
Concentration 1 mg/ml when reconstitute in 100 ul
Purity Purified from ascites
Size 100 µg
Source Species Mouse
Antibody
Immunogen Sphingosine-1-phosphate receptor 1
Clonality Monoclonal
Isotype IgG
Form Freeze dry solid
Storage Instructions Store at 4°C.
Storage Buffer Preservative: None; Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, when reconstitute with 100 ul di water
Species Reactivity Human SPR-1

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