Store-operated calcium channels (SOCs) play essential functions in various physiological processes. Orai1 (also named CRACM1) is a critical molecular component of SOCs. Orai1 protein is a ~35kDa plasma membrane protein with 4 transmembrane domains. Human patients with a severe combined immunodeficiency (SCID) syndrome possess point mutations in Orai1 gene.
Orai1-L2 antibody recognizes Orai1 from human.
Western blot analysis of Orai1 protein. Human Orai1 plasmid DNA was transiently transfected into HEK-293 cells. Whole-cell lysate was used for western blot in the absence (A) or presence (B) of antigen peptide.
|Purity||Immunogen affinity purified|
|Immunogen||A peptide from the extracellular loop 2 region of human Orai1|
|Storage Instructions||Store at -20°C. Avoid repeated freeze / thaw cycles.|
|Storage Buffer||Preservative: 0.01% sodium azide; Constituents: 50mM NaHCO3-Glycine, pH 7.4, 150 mM NaCl|
|Recommended Dilutions||ELISA, 1:1000-1:5000; WB, 1:1000-1:2000; IHC, 1:100-1:200|
|Species Reactivity||Orai1-L2 antibody recognizes Orai1 from human.|