p53 protein acts as a tumor suppressor in many tumor types and induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Defects in TP53 are found in many types of cancers.
ELISA, WB, IHC, IF
Anti-TP53(R282W) antibody recognizes TP53(R282W) of vertebrates.
Western blot analysis of recombinant TP53(R282W) and wildtype proteins. Purified His-tagged TP53(R282W) protein and wildtype protein were blotted with anti-TP53(R282W) rabbit antibody (Cat. #NEBA10073).
|Applications||ELISA, WB, IHC, IF|
|Purity||Purified from serum|
|Immunogen||A synthetic peptide near the C-terminus of human TP53 which includes the mutation of R282W|
|Storage Instructions||Store at -20°C. Avoid repeated freeze / thaw cycles.|
|Storage Buffer||Preservative: No; Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol|
|Recommended Dilutions||ELISA, 1:1000-1:5000; WB, 1:1000-1:5000; IHC, 1:50-1:100|
|Species Reactivity||Anti-TP53(R282W) antibody recognizes TP53(R282W) of vertebrates.|