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Pathology and Immunohistochemistry
 

QC-Dots Control Slides

These are quality control slides designed to provide on-slide staining controls for IHC staining and in situ hybridization applications.  QC-Dots slides are pre-spotted with cells that are carefully selected to serve as both positive and negative controls in an IHC or ISH application.  The patent-pending technology was developed over many years and validated for many IHC biomarkers.  QC-Dots slides can be used for establishing optimal testing conditions for new antibodies or used routinely replacing blank microscope slides.

How It Works

Control spots are carefully designed and developed for different IHC or ISH applications, QC-Dots slides can be used just like any blank microscopic slides except positive and negative controls are already there.

Digital Pathology

In a time when many IHC staining images are scanned/digitized and analysed using imaging analysis software, QC-Dots control slides enable automated image analysis and read-out.  By including positive and negative control features on the same slide where the sample is also stained, QC Dots slides make it possible for image analysis software to analyze control signals and sample signals at the same time.  

QC Dots control slide enables digital pathology


Different QC-Dots Control Slides:

QC dot CA control slide

QC-Dots CA

This is a slide designed for cancer IHC application; The slide contains 9 carefully selected cancer and normal cells spots, those cell spots can be used as positive and negative controls for IHC staining of cancer cells and tissues.  

QC dot ID control slide

QC-Dots ID

This is a slide designed for viral IHC/ISH applications; The slide contains spots of cells that infected by 8 different viruses and one spot of cells with no viral infection as the negative control.   

QC-Dots HP

is a slide designed for H. pylori staining; The slide contains two spots: one with cells infected by H. pylori, one with no infection.  The slide is designed for H. pylori IHC/ISH applications.

Anti-Abl (Y253H) Mouse Monoclonal Antibody, 100 µl (26154) Cancer Research NewEast Biosciences NEBA10177
Background V-abl Abelson murine leukemia viral oncogene homolog 1 also known as ABL1, is a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, stress response and cell migration. Deficient in Abl can cause seve..
Anti-Active Arf6 Mouse Monoclonal Antibody, 30 µl (26918) Signal Transduction NewEast Biosciences NEBA10223
Background ARF6 ( ADP- ribosylation factor 6 ) is a member of the ARF superfamily. ARF genes encode small GTPases that increase the ADP- ribosyltransferase activity of cholera toxin and are critical for vesicular trafficking as activators of phospholipase D. Arf6 regulate s membrane trafficki..
Anti-Active Arl1 Mouse Monoclonal Antibody, 30 µl (26924) Signal Transduction NewEast Biosciences NEBA10229
Background Arl1 (Arf-like 1) localizes to the Golgi complex, where it is believed to recruit effector proteins to the trans-Golgi network. Golgi-localized proteins golgin-97 and golgin-245 have been shown as Arl1 effectors. Additional Arl1 effectors include the GARP (Golgi-associated retrograde pro..
Anti-Active Arl3 Mouse Monoclonal Antibody, 30 µl (26925) Signal Transduction NewEast Biosciences NEBA10230
Background Arl3 (Arf-like 3) is an Arf family protein. Arl3 binds microtubules to alter specific aspects of cytokinesis. It has been proposed that retinitis pigmentosa 2 functions in concert with Arl3 to link the cell membrane and the cytoskeleton in photoreceptors as part of the cell signaling or ..
Anti-Active Cdc42 Mouse Monoclonal Antibody, 30 µl (26905) Signal Transduction NewEast Biosciences NEBA10212
Background Small GTPases are a superfamily of cellular signaling regulators. Cdc42 belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Cdc42, and the hydrolysis of GTP to GDP renders it inactive. GTP hydr..
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Anti-Active Gα13-GTP Mouse Monoclonal Antibody, 30 µl (26902) Signal Transduction NewEast Biosciences NEBA10209
Background Heterotrimeric G proteins are essential cellular signal transducers. Gα13 is one of the G proteins that could mediate cell migration and angiogenesis. Other biochemical and physiological functions of Gα13 are being explored. Tested Applications IP, IHC Source Species Mouse Species R..
Anti-Active Gαi Mouse Monoclonal Antibody, 30 µl (26901) Signal Transduction NewEast Biosciences NEBA10208
Background Heterotrimeric G proteins are critical cellular signal transducers. Gαi represents one sub-family of G proteins that could mediate the inhibition of adenylyl cyclases. Other biochemical and physiological functions of Gαi proteins are being explored. Tested Applications IP, IHC Sour..
Anti-Active Gαo Mouse Monoclonal Antibody, 30 µl (26907) Signal Transduction NewEast Biosciences NEBA10214
Background Heterotrimeric G proteins are critical cellular signal transducers. Gαo represents one sub-family of G proteins that could mediate the inhibition of adenylyl cyclases. Other biochemical and physiological functions of Gαo proteins are being explored. Tested Applications IP, IHC Source ..
Anti-Active Gαs Mouse Monoclonal Antibody, 30 µl (26906) Signal Transduction NewEast Biosciences NEBA10213
Background Heterotrimeric G proteins are critical cellular signal transducers. Gαs represents one sub-family of G proteins that could mediate the stimulation of adenylyl cyclases. Tested Applications IP, IHC Source Species Mouse Species Reactivity Anti-active Gαs antibody recognizes active Gα..
Anti-Active Gαz Mouse Monoclonal Antibody, 30 µl (26908) Signal Transduction NewEast Biosciences NEBA10215
Background Heterotrimeric G proteins are critical cellular signal transducers. Gαz represents one sub-family of G proteins that could mediate the inhibition of adenylyl cyclases. Other biochemical and physiological functions of Gαz proteins are being explored. Tested Applications IP, IHC Source ..
Anti-Active Rab11 Mouse Monoclonal Antibody, 30 µl (26919) Signal Transduction NewEast Biosciences NEBA10224
Background Small GTPases of the Rab- family are crucial elements of the machinery that controls membrane traffic. Rab11 has been shown to control traffic through the recycling endosome. Tested Applications IP, IHC Source Species Mouse Species Reactivity Anti-active Rab11 antibody recogniz..
Anti-Active Rab3 Mouse Monoclonal Antibody, 30 µl (26920) Signal Transduction NewEast Biosciences NEBA10225
Background Rab3 is a member of the Rab-family GTPases and is specifically targeted to synaptic vesicles. Tested Applications IP, IHC, IF Source Species Mouse Species Reactivity Anti-active Rab3 antibody recognizes active Rab3 proteins of vertebrates. Datasheet   Immunoprecipitatio..
Anti-Active Rab35 Mouse Monoclonal Antibody, 30 µl (26922) Signal Transduction NewEast Biosciences NEBA10227
Background The Rab family of GTPases regulates eukaryotic vesicular membrane traffic. Rab35 is with both plasma membrane and endosomal localization, and has been implicated in diverse processes that include T-cell receptor recycling, oocyte yolk protein recycling and cytokinesis. Rab35 regulates ne..
Anti-Active Rab4 Mouse Monoclonal Antibody, 30 µl (26921) Signal Transduction NewEast Biosciences NEBA10226
Background Rab-4 belongs to the small GTPase Rab family. It interacts with RAB11FIP1, RABEP1, ZFYVE20, RUFY1, SGSM1, SGSM2 and SGSM3. It participates in protein transport and in vesicular traffic. Tested Applications IP, IHC Source Species Mouse Species Reactivity Anti-active Rab4 antibody re..
Anti-Active Rab5 Mouse Monoclonal Antibody, 30 µl (26911) Signal Transduction NewEast Biosciences NEBA10218
Background Rab5 is a member of Rab-family GTPases. Rab5 is a rate-limiting component of the machinery regulating the kinetics of membrane traffic in the early endocytic pathway. Tested Applications IP, IHC Source Species Mouse Species Reactivity Anti-active Rab5 antibody recognizes active Rab..
Pathology, Immunohistochemistry, Applications
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