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Antibodies for Oncogenes

Gene name

Abs against wild type

Abs against mutants

Abl

 

Abl (Y253H) McAb

AKT1

AKT1 pAb

AKT1 (E49K) McAb

ALK

ALK pAb

ALK (C1156Y) McAb, ALK (R1275Q) McAb, EML4-ALK McAb

ATM

ATM pAb

ATM (F858L), ATM (Q2442P), ATM (R2443Q)

Bag1

Bag1 McAb,

Bag1 pAb, internal immunogen,

Bag1 pAb, N-terminal immunogen

 

BCL-2

BCL-2 pAb

 

B-Raf

B-Raf McAb,  B-Raf pAb

B-Raf (G469E) McAb, B-Raf (N581S) McAb,

B-Raf (V600D) McAb, B-Raf (V600E) McAb,

B-Raf (V600K) McAb, B-Raf (V600R) McAb

CTNNB1

 

CTNNB1 (S37F) McAb, CTNNB1 (S37Y) McAb, CTNNB1 (T41A) McAb

EGFR

EGFR pAb

EGFR (A839T) McAB, EGFR (D761Y) McAb, EGFR (G719A) McAb, EGFR (G719S) McAb, EGFR (G863D) McAb, EGFR (L858Q) McAb, EGFR (L858R) McAb, EGFR (L861Q) McAb, EGFR (N826S) McAb, EGFR (V769L) McAb, EGFR (vIII) McAb

ER1

ER1 pAb

 

ErbB2

ERBB2 McAb,

ERBB2 pAb, C-terminal immunogen,

ErbB2 pAb, internal immunogen

ErbB2 (V777A)

GRB7

GRB7 pAb

 

IDH1

 

IDH1 (R132H) McAb, IDH1 (R132S) McAb,

IDH2

 
 

IDH2 (R140Q) McAb, IDH2 (R172G) McAb, IDH2 (R172H) McAb, IDH2 (R172K) McAb, IDH2 (R172W) McAb

MEK1

 

MEK1 (I111S) McAb, MEK1 (N382H) McAb, MEK1 (Q56P) McAb

PIK3CA

PIK3CA McAb

PIK3CA (E545K) pAb, PIK3CA (H1047R) pAb, PIK3CA (Q546K) McAb

Ras

 

HRAS (G13A) McAb, RAS (A146T) McAb,

Ras (G12D) McAb, RAS (G12S) McAb,

Ras (G13D) McAb, Ras (Q61H) McAb,

Ras (Q61L) McAb, Ras (Q61R) McAb

STK11

STK11 pAb, STK11 McAb

 

STK15

STK15 pAb

 

TP53

TP53 pAb

TP53 (R175H) McAb, TP53 (R175H) pAb,

TP53 (R282W) McAb, TP53 (R282W) pAb

β-catenin

β-catenin pAb

β-catenin (A43V) McAb, β-catenin (E53K) McAb, β-catenin (G38D) McAb, β-catenin (G48D) McAb

 

Anti-Abl (Y253H) Mouse Monoclonal Antibody, 100 µl (26154) Cancer Research NewEast Biosciences NEBA10177
Background V-abl Abelson murine leukemia viral oncogene homolog 1 also known as ABL1, is a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, stress response and cell migration. Deficient in Abl can cause seve..
Anti-AKT1 (E49K) Mouse Monoclonal Antibody, 100 µl (26137) Cancer Research NewEast Biosciences NEBA10170
Background AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinases, which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. Its function is mediated through serine and/or threonine phosphorylat..
Anti-AKT1 Rabbit Polyclonal Antibody, 100 µl (21274) Cancer Research NewEast Biosciences NEBA10089
Background AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. Its function is mediated through serine and/or threonine phosphory..
Anti-ALK (C1156Y) Mouse Monoclonal Antibody, 100 µl (26226) Cancer Research NewEast Biosciences NEBA10200
Background Anaplastic lymphoma kinase (ALK) also known as CD246 (cluster of differentiation 246) is a tyrosine kinase receptor that plays an important role in the development of the brain and nervous systems. Deficiencies in ALK, which most commonly as a fusion with other genes, are indicated in ca..
Anti-ALK (R1275Q) Mouse Monoclonal Antibody, 100 µl (26151) Cancer Research NewEast Biosciences NEBA10176
Background Anaplastic lymphoma kinase (ALK) also known as CD246 (cluster of differentiation 246) is a tyrosine kinase receptor that plays an important role in the development of the brain and nervous systems. Deficiencies in ALK, which most commonly as a fusion with other genes, are indicated in ca..
Anti-ALK Rabbit Polyclonal Antibody, 100 µl (21280) Cancer Research NewEast Biosciences NEBA10093
Background Anaplastic lymphoma kinase (ALK) also known as ALK tyrosine kinase receptor or CD246 (cluster of differentiation 246) is a neuronal orphan receptor tyrosine kinase. ALK is essentially and transiently expressed in specific regions of the central and peripheral nervous systems and plays an..
Anti-ATM (F858L) Mouse Monoclonal Antibody, 100 µl (26141) Cancer Research NewEast Biosciences NEBA10173
Background Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activ..
Anti-ATM (Q2442P) Mouse Monoclonal Antibody, 100 µl (26142) Cancer Research NewEast Biosciences NEBA10174
Background Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activ..
Anti-ATM (R2443Q) Mouse Monoclonal Antibody, 100 µl (26143) Cancer Research NewEast Biosciences NEBA10175
Background Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activ..
Anti-ATM (R3008H) Mouse Monoclonal Antibody, 100 µl (26140) Cancer Research NewEast Biosciences NEBA10172
Background Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activ..
Anti-ATM Rabbit Polyclonal Antibody, 100 µl (21276) Cancer Research NewEast Biosciences NEBA10090
Background Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activ..
Anti-B-RAF (G469E) Mouse Monoclonal Antibody, 100 µl (26196) Signal Transduction NewEast Biosciences NEBA10197
Background BRAF belongs to a family of serine-threonine protein kinases.BRAF belongs to a family of serine-threonine protein kinases As a part of a signaling pathway known as the the RAS/MAPK pathway, it plays an important part in many cellular processes. The processes include cell proliferation,..
Anti-B-Raf (N581S) Mouse Monoclonal Antibody, 100 µl (26109) Signal Transduction NewEast Biosciences NEBA10155
Background B-Raf is a member of the Raf family of Ser/Thr protein kinases. It functions downstream of Ras to regulate the MAP kinase signaling pathway. Mutations in the BRAF gene cause diseases. Inherited mutations in BRAF cause cardiofaciocutaneous syndrome. Acquired mutations in BRAF have been ..
Anti-B-Raf (V600D) Mouse Monoclonal Antibody, 100 µl (26184) Signal Transduction NewEast Biosciences NEBA10191
Background B-Raf is a member of the Raf family of Ser/Thr protein kinases. It functions downstream of Ras to regulate the MAP kinase signaling pathway. Mutations in the BRAF gene cause diseases. Inherited mutations in BRAF cause cardiofaciocutaneous syndrome. Acquired mutations in BRAF have been ..
Anti-B-Raf (V600E) Mouse Monoclonal Antibody, 100 µl (26039) Signal Transduction NewEast Biosciences NEBA10126
Background B-Raf is a member of the Raf family of Ser/Thr protein kinases. It functions downstream of Ras to regulate the MAP kinase signaling pathway. Mutations in the BRAF gene cause diseases. Inherited mutations in BRAF cause cardiofaciocutaneous syndrome. Acquired mutations in BRAF have been ..
Antibodies, Oncogenes, Primary
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