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Anti-ER1 Rabbit Polyclonal Antibody, 100 µl (21220) Signal Transduction NewEast Biosciences NEBA10080
Background Estrogen receptor (ER) is a member of the nuclear hormone family of intracellular receptors. There are two different forms of the estrogen receptor, usually referred to as α and β, each encoded by a separate genes (ESR1 and ESR2, respectively). Upon activation by estrogen, the estrogen r..
Anti-ErbB2 (V777A) mouse monoclonal Antibody, 100 µl (26080) Signal Transduction NewEast Biosciences NEBA10145
Background The ErbB family is composed of four plasma membrane-bound receptor tyrosine kinases. Amplification or over-expression of the ERBB2 gene occurs in approximately 30% of breast cancers. HER2 is encoded by ERBB2, a known proto-oncogene located at the long arm of human chromosome 17(17q21-q22..
Anti-ERBB2 Mouse Monoclonal Antibody, 100 µl (26127) Signal Transduction NewEast Biosciences NEBA10163
Background The HER-2/neu oncogene, a member of the epidermal growth factor receptor or erb-B gene-like family, encodes a transmembrane tyrosine kinase receptor that mediates extracellular signals activated by epidermal growth factors. Her2 abnormal has been strongly associated with many malignant t..
Anti-ERBB2 Rabbit polyclonal Antibody, C-terminal immunogen, 100 µl (21200) Signal Transduction NewEast Biosciences NEBA10074
Background The HER-2/neu oncogene, a member of the epidermal growth factor receptor or erb-B gene-like family, encodes a transmembrane tyrosine kinase receptor that mediates extracellular signals activated by epidermal growth factors. Her2 abnormal has been strongly associated with many malignant t..
Anti-ErbB2 Rabbit Polyclonal Antibody, internal immunogen, 100 µl (21202) Signal Transduction NewEast Biosciences NEBA10075
Background The ErbB family is composed of four plasma membrane-bound receptor tyrosine kinases. Amplification or over-expression of the ERBB2 gene occurs in approximately 30% of breast cancers. HER2 is encoded by ERBB2, a known proto-oncogene located at the long arm of human chromosome 17(17q21-q22..
Anti-EYA2 Mouse Monoclonal Antibody, 100 µl (26096) Cancer Research NewEast Biosciences NEBA10154
Background EYA2 may be involved in development of the eye. It promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. ..
Anti-EYA2 Mouse Monoclonal Antibody, N-terminal immunogen, 100 µl (26052) Cancer Research NewEast Biosciences NEBA10132
Background EYA2 may be involved in development of the eye. It promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. ..
Anti-EYA2 Rabbit Polyclonal Antibody, 100 µl (21128) Cancer Research NewEast Biosciences NEBA10063
Background EYA2 (eyes absent homolog 2) functions as a tyrosine phosphatase that specifically dephosphorylates Tyr-142 of histone H2AX. EYA2 promotes efficient DNA repair and coactivates SIX1. Together with SIX1 and DACH2, EYA2 seems to be involved in myogenesis. Tested Applications ELISA, WB, IH..
Anti-Fascin Mouse Monoclonal Antibody, internal immunogen, 100 µl (26013) Cell Biology NewEast Biosciences NEBA10108
Background Fascin is an ~58 kDa monomeric actin filament bundling protein. It is required to maximally cross-link the actin filaments into straight, compact, and rigid bundles, and contributes to the formation of filopodia that are critical for cell migration. Elevated levels of fascin have been fo..
Anti-Fascin Mouse Monoclonal Antibody, N-terminal immunogen, 100 µl (26012) Cell Biology NewEast Biosciences NEBA10107
Background Fascin is an ~58 kDa monomeric actin filament bundling protein. It is required to maximally cross-link the actin filaments into straight, compact, and rigid bundles, and contributes to the formation of filopodia that are critical for cell migration. Elevated levels of fascin have been fo..
Anti-GAPDH Rabbit Polyclonal Antibody, 100 µl (21012) Cancer Research NewEast Biosciences NEBA10009
Background Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, an important energy-yielding step in carbohydrate metabolism. Additional functions of GAPDH include acting as a uricil DNA glycosylase, activating transcript..
Anti-GRB7 Mouse Monoclonal Antibody, 100 µl (26133) Signal Transduction NewEast Biosciences NEBA10167
Background Grb7 is an adaptor protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. It plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Grb7 gene is commonly co-amplified (present in excess copies) in ..
Anti-GRB7 Rabbit Polyclonal Antibody, 100 µl (21218) Signal Transduction NewEast Biosciences NEBA10079
Background Grb7 is an adaptor protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. It plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Grb7 gene is commonly co-amplified (present in excess copies) in ..
Anti-Gα12 Mouse Monoclonal Antibody, 100 µl (26026) Signal Transduction NewEast Biosciences NEBA10118
Background Heterotrimeric G proteins are essential cellular signal transducers. Gα12 is a member of the G12/13 subfamily of G proteins. Biochemical and physiological functions of Gα12 are being explored. Tested Applications ELISA, WB, IHC, IP Source Species Mouse Species Reactivity Gα12 antib..
Anti-Gα13 Mouse Monoclonal Antibody, 100 µl (26004) Signal Transduction NewEast Biosciences NEBA10100
Background Heterotrimeric G proteins are essential cellular signal transducers. Gα13 is one of the G proteins that could mediate cell migration and angiogenesis. Other biochemical and physiological functions of Gα13 are being explored. Tested Applications ELISA, WB, IHC Source Species Mouse Sp..
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