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Anti-Abl (Y253H) Mouse Monoclonal Antibody, 100 µl (26154) Cancer Research NewEast Biosciences NEBA10177
Background V-abl Abelson murine leukemia viral oncogene homolog 1 also known as ABL1, is a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, stress response and cell migration. Deficient in Abl can cause seve..
Anti-Active Arf6 Mouse Monoclonal Antibody, 30 µl (26918) Signal Transduction NewEast Biosciences NEBA10223
Background ARF6 ( ADP- ribosylation factor 6 ) is a member of the ARF superfamily. ARF genes encode small GTPases that increase the ADP- ribosyltransferase activity of cholera toxin and are critical for vesicular trafficking as activators of phospholipase D. Arf6 regulate s membrane trafficki..
Anti-Active Arl1 Mouse Monoclonal Antibody, 30 µl (26924) Signal Transduction NewEast Biosciences NEBA10229
Background Arl1 (Arf-like 1) localizes to the Golgi complex, where it is believed to recruit effector proteins to the trans-Golgi network. Golgi-localized proteins golgin-97 and golgin-245 have been shown as Arl1 effectors. Additional Arl1 effectors include the GARP (Golgi-associated retrograde pro..
Anti-Active Arl3 Mouse Monoclonal Antibody, 30 µl (26925) Signal Transduction NewEast Biosciences NEBA10230
Background Arl3 (Arf-like 3) is an Arf family protein. Arl3 binds microtubules to alter specific aspects of cytokinesis. It has been proposed that retinitis pigmentosa 2 functions in concert with Arl3 to link the cell membrane and the cytoskeleton in photoreceptors as part of the cell signaling or ..
Anti-Active Cdc42 Mouse Monoclonal Antibody, 30 µl (26905) Signal Transduction NewEast Biosciences NEBA10212
Background Small GTPases are a superfamily of cellular signaling regulators. Cdc42 belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Cdc42, and the hydrolysis of GTP to GDP renders it inactive. GTP hydr..
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Anti-Active Gα13-GTP Mouse Monoclonal Antibody, 30 µl (26902) Signal Transduction NewEast Biosciences NEBA10209
Background Heterotrimeric G proteins are essential cellular signal transducers. Gα13 is one of the G proteins that could mediate cell migration and angiogenesis. Other biochemical and physiological functions of Gα13 are being explored. Tested Applications IP, IHC Source Species Mouse Species R..
Anti-Active Gαi Mouse Monoclonal Antibody, 30 µl (26901) Signal Transduction NewEast Biosciences NEBA10208
Background Heterotrimeric G proteins are critical cellular signal transducers. Gαi represents one sub-family of G proteins that could mediate the inhibition of adenylyl cyclases. Other biochemical and physiological functions of Gαi proteins are being explored. Tested Applications IP, IHC Sour..
Anti-Active Gαo Mouse Monoclonal Antibody, 30 µl (26907) Signal Transduction NewEast Biosciences NEBA10214
Background Heterotrimeric G proteins are critical cellular signal transducers. Gαo represents one sub-family of G proteins that could mediate the inhibition of adenylyl cyclases. Other biochemical and physiological functions of Gαo proteins are being explored. Tested Applications IP, IHC Source ..
Anti-Active Gαs Mouse Monoclonal Antibody, 30 µl (26906) Signal Transduction NewEast Biosciences NEBA10213
Background Heterotrimeric G proteins are critical cellular signal transducers. Gαs represents one sub-family of G proteins that could mediate the stimulation of adenylyl cyclases. Tested Applications IP, IHC Source Species Mouse Species Reactivity Anti-active Gαs antibody recognizes active Gα..
Anti-Active Gαz Mouse Monoclonal Antibody, 30 µl (26908) Signal Transduction NewEast Biosciences NEBA10215
Background Heterotrimeric G proteins are critical cellular signal transducers. Gαz represents one sub-family of G proteins that could mediate the inhibition of adenylyl cyclases. Other biochemical and physiological functions of Gαz proteins are being explored. Tested Applications IP, IHC Source ..
Anti-Active Rab11 Mouse Monoclonal Antibody, 30 µl (26919) Signal Transduction NewEast Biosciences NEBA10224
Background Small GTPases of the Rab- family are crucial elements of the machinery that controls membrane traffic. Rab11 has been shown to control traffic through the recycling endosome. Tested Applications IP, IHC Source Species Mouse Species Reactivity Anti-active Rab11 antibody recogniz..
Anti-Active Rab3 Mouse Monoclonal Antibody, 30 µl (26920) Signal Transduction NewEast Biosciences NEBA10225
Background Rab3 is a member of the Rab-family GTPases and is specifically targeted to synaptic vesicles. Tested Applications IP, IHC, IF Source Species Mouse Species Reactivity Anti-active Rab3 antibody recognizes active Rab3 proteins of vertebrates. Datasheet   Immunoprecipitatio..
Anti-Active Rab35 Mouse Monoclonal Antibody, 30 µl (26922) Signal Transduction NewEast Biosciences NEBA10227
Background The Rab family of GTPases regulates eukaryotic vesicular membrane traffic. Rab35 is with both plasma membrane and endosomal localization, and has been implicated in diverse processes that include T-cell receptor recycling, oocyte yolk protein recycling and cytokinesis. Rab35 regulates ne..
Anti-Active Rab4 Mouse Monoclonal Antibody, 30 µl (26921) Signal Transduction NewEast Biosciences NEBA10226
Background Rab-4 belongs to the small GTPase Rab family. It interacts with RAB11FIP1, RABEP1, ZFYVE20, RUFY1, SGSM1, SGSM2 and SGSM3. It participates in protein transport and in vesicular traffic. Tested Applications IP, IHC Source Species Mouse Species Reactivity Anti-active Rab4 antibody re..
Anti-Active Rab5 Mouse Monoclonal Antibody, 30 µl (26911) Signal Transduction NewEast Biosciences NEBA10218
Background Rab5 is a member of Rab-family GTPases. Rab5 is a rate-limiting component of the machinery regulating the kinetics of membrane traffic in the early endocytic pathway. Tested Applications IP, IHC Source Species Mouse Species Reactivity Anti-active Rab5 antibody recognizes active Rab..
Anti-Active Rab7 Mouse Monoclonal Antibody, 30 µl (26923) Signal Transduction NewEast Biosciences NEBA10228
Background Rab7 belongs to the Rab family of small GTPases. Rab7 is located in the late endosome, lysosome, cytoplasmic vesicle, phagosome and melanosome. It is involved in the late endocytic transport and contributes to the maturation of phagosomes. Tested Applications IP, IHC, IF Source Specie..
Anti-Active Rac-GTP Mouse Monoclonal Antibody, 30 µl (26903) Signal Transduction NewEast Biosciences NEBA10210
Background Small GTPases are a superfamily of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Rac, and the hydrolysis of GTP to GDP renders it inactive.Currently the..
Anti-Active Ral Mouse Monoclonal Antibody, 30 µl (26913) Signal Transduction NewEast Biosciences NEBA10220
Background The Ras- like small G proteins, RalA and RalB, are important components of Ras signaling pathways, implicated in the initiation and m aintenance of tumorigenic transformation, as well as vesicle transport, apoptosis, transcription, cell migration, and cell proliferation. Tested App..
Anti-Active Ran Mouse Monoclonal Antibody, 30 µl (26915) Signal Transduction NewEast Biosciences NEBA10221
Background Ran (Ras-related nuclear protein) is a member of the Ras-superfamily GTPases. Ran is invovled in the transport of proteins across the nuclear envelope, as well as in microtubule organization during mitosis. Tested Applications IP, IHC Source Species Mouse Species Reactivity Anti-ac..
Anti-Active Rap1 Mouse Monoclonal Antibody, 30 µl (26912) Signal Transduction NewEast Biosciences NEBA10219
Background Small GTPases are a superfamily of cellular signaling regulators. Rap family members (Rap1A, Rap1B, Rap2A, Rap2B, and Rap2C) are Ras-like GTPases that regulate cell proliferation, differentiation, apoptosis and adhesion mechanisms. Rap1 (Ras-proximate-1) regulates apoptosis through inter..
Anti-Active Ras Mouse Monoclonal Antibody, 30 µl (26909) Signal Transduction NewEast Biosciences NEBA10216
Background Small GTPases are a superfamily of cellular signaling regulators. Ras belongs to the Ras sub-family of GTPases that regulate cell proliferation, cell motility, and gene transcription. GTP binding increases the activity of Ras, and the hydrolysis of GTP to GDP renders it inactive. GTP hyd..
Anti-Active Rheb Mouse Monoclonal Antibody, 30 µl (26910) Signal Transduction NewEast Biosciences NEBA10217
Background Small GTPases are a superfamily of cellular signaling regulators. Rheb is a member of the Ras-superfamily GTPases. Rheb has been shown to interact with C-Raf, Mammalian target of rapamycin (mTOR), TSC2, Ataxia telangiectasia mutated (ATM), KIAA1303 and Ataxia telangiectasia and Rad3 rela..
Anti-Active RhoA Mouse Monoclonal Antibody, 30 µl (26904) Signal Transduction NewEast Biosciences NEBA10211
Background Small GTPases are a superfamily of cellular signaling regulators. RhoA belongs to the Rho sub-family of GTPases. Rho proteins play critical roles in many actin cytoskeleton- dependent processes including platelet aggregation, cell motility, contraction, and cytokinesis. It regulates the ..
Anti-Active Sar1 Mouse Monoclonal Antibody, 30 µl (26916) Signal Transduction NewEast Biosciences NEBA10222
Background Small GTPases are a superfamily of cellular signaling regulators. Sar1 is a member of these small GTPases. Sar1 functions as a molecular switch to control protein–protein and protein–lipid interactions that direct vesicle budding from the ER. Tested Applications IP, IHC Source Sp..
Anti-AKT1 (E49K) Mouse Monoclonal Antibody, 100 µl (26137) Cancer Research NewEast Biosciences NEBA10170
Background AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinases, which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. Its function is mediated through serine and/or threonine phosphorylat..
Anti-AKT1 Rabbit Polyclonal Antibody, 100 µl (21274) Cancer Research NewEast Biosciences NEBA10089
Background AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. Its function is mediated through serine and/or threonine phosphory..
Anti-Albumin Mouse Monoclonal Antibody, 100 µl (26090) Signal Transduction NewEast Biosciences NEBA10152
Background Albumin belongs to the ALB/AFP/VDB family. It comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones, and also plays a role in stabilizing extracellular fluid volume. Defects in Albumin will ca..
Anti-Albumin Rabbit Polyclonal Antibody, 100 µl (21112) Signal Transduction NewEast Biosciences NEBA10057
Background Serum albumin is the most abundant blood plasma protein in mammals. Albumin is essential for maintaining the osmotic pressure needed for proper distribution of body fluids between intravascular compartments and body tissues. It also acts as a plasma carrier by non-specifically binding se..
Anti-ALK (C1156Y) Mouse Monoclonal Antibody, 100 µl (26226) Cancer Research NewEast Biosciences NEBA10200
Background Anaplastic lymphoma kinase (ALK) also known as CD246 (cluster of differentiation 246) is a tyrosine kinase receptor that plays an important role in the development of the brain and nervous systems. Deficiencies in ALK, which most commonly as a fusion with other genes, are indicated in ca..
Anti-ALK (R1275Q) Mouse Monoclonal Antibody, 100 µl (26151) Cancer Research NewEast Biosciences NEBA10176
Background Anaplastic lymphoma kinase (ALK) also known as CD246 (cluster of differentiation 246) is a tyrosine kinase receptor that plays an important role in the development of the brain and nervous systems. Deficiencies in ALK, which most commonly as a fusion with other genes, are indicated in ca..
Anti-ALK Rabbit Polyclonal Antibody, 100 µl (21280) Cancer Research NewEast Biosciences NEBA10093
Background Anaplastic lymphoma kinase (ALK) also known as ALK tyrosine kinase receptor or CD246 (cluster of differentiation 246) is a neuronal orphan receptor tyrosine kinase. ALK is essentially and transiently expressed in specific regions of the central and peripheral nervous systems and plays an..
Anti-ApoA1 Rabbit Polyclonal Antibody, 100 µl (21113) Cell Biology NewEast Biosciences NEBA10058
Background Apolipoprotein A-I belongs to the apolipoprotein A1/A4/E family. It is the major protein component of high density lipoprotein (HDL) in plasma and has a specific role in lipid metabolism. ApoA1 participates in the reverse transport of cholesterol from tissues to the liver for excretion b..
Anti-Apolipoprotein A1 Mouse Monoclonal Antibody, 100 µl (26025) Cell Biology NewEast Biosciences NEBA10117
Background Apolipoprotein A1 is the major protein component of high-density lipoprotein (HDL) (“good cholesterol”) in plasma. Apolipoprotein A1 helps to clear cholesterol from arteries. Tested Applications ELISA, WB, IHC, IP Source Species Mouse Species Reactivity Apolipoprotein A1 antibody r..
Anti-Apolipoprotein A1 Mouse Monoclonal Antibody, C-terminal immunogen, 100 µl (26023) Cell Biology NewEast Biosciences NEBA10116
Background Apolipoprotein A1 is the major protein component of high-density lipoprotein (HDL) (“good cholesterol”) in plasma. Apolipoprotein A1 helps to clear cholesterol from arteries. Tested Applications ELISA, WB, IHC Source Species Mouse Species Reactivity Apolipoprotein A1 antibody recog..
Anti-Arf1 Mouse Monoclonal Antibody, 100 µl (26019) Signal Transduction NewEast Biosciences NEBA10113
Background ARF1 (ADP-ribosylation factor 1) is a member of the ARF superfamily. ARF genes encode small GTPases that increase the ADP-ribosyltransferase activity of cholera toxin and are critical for vesicular trafficking as activators of phospholipase D. ARF1 protein is localized to the Golgi appar..
Anti-Arf1 Rabbit Polyclonal Antibody, 100 µl (21283) Signal Transduction NewEast Biosciences NEBA10096
Background ARF1 (ADP-ribosylation factor 1) is a member of the ARF superfamily. ARF genes encode small GTPases that increase the ADP-ribosyltransferase activity of cholera toxin and are critical for vesicular trafficking as activators of phospholipase D. ARF1 protein is localized to the Golgi appar..
Anti-Arf1 Rabbit Polyclonal Antibody, internal immunogen, 100 µl (21030) Signal Transduction NewEast Biosciences NEBA10019
Background ARF1 (ADP-ribosylation factor 1) is a member of the ARF superfamily. ARF genes encode small GTPases that increase the ADP-ribosyltransferase activity of cholera toxin and are critical for vesicular trafficking as activators of phospholipase D. ARF1 protein is localized to the Golgi appar..
Anti-Arf6 Mouse Monoclonal Antibody, 100 µl (26029) Signal Transduction NewEast Biosciences NEBA10120
Background ARF6 (ADP-ribosylation factor 6) is a member of the ARF superfamily. ARF genes encode small GTPases that increase the ADP-ribosyltransferase activity of cholera toxin and are critical for vesicular trafficking as activators of phospholipase D. Arf6 regulates membrane trafficking and the ..
Anti-Arf6 Rabbit Polyclonal Antibody, 100 µl (21032) Signal Transduction NewEast Biosciences NEBA10020
Background ARF6 (ADP-ribosylation factor 6) is a member of the ARF superfamily. ARF genes encode small GTPases that increase the ADP-ribosyltransferase activity of cholera toxin and are critical for vesicular trafficking as activators of phospholipase D. Arf6 regulates membrane trafficking and the ..
Anti-Arl1 Mouse Monoclonal Antibody, 100 µl (26056) Signal Transduction NewEast Biosciences NEBA10135
Background Arl1 (Arf-like 1) localizes to the Golgi complex, where it is believed to recruit effector proteins to the trans-Golgi network. Golgi-localized proteins golgin-97 and golgin-245 have been shown as Arl1 effectors. Additional Arl1 effectors include the GARP (Golgi-associated retrograde pro..
Anti-Arl3 Mouse Monoclonal Antibody, 100 µl (26070) Signal Transduction NewEast Biosciences NEBA10140
Background Arl3 (Arf-like 3) is an Arf family protein. Arl3 binds microtubules to alter specific aspects of cytokinesis. It has been proposed that retinitis pigmentosa 2 functions in concert with Arl3 to link the cell membrane and the cytoskeleton in photoreceptors as part of the cell signaling or ..
Anti-ATM (F858L) Mouse Monoclonal Antibody, 100 µl (26141) Cancer Research NewEast Biosciences NEBA10173
Background Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activ..
Anti-ATM (Q2442P) Mouse Monoclonal Antibody, 100 µl (26142) Cancer Research NewEast Biosciences NEBA10174
Background Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activ..
Anti-ATM (R2443Q) Mouse Monoclonal Antibody, 100 µl (26143) Cancer Research NewEast Biosciences NEBA10175
Background Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activ..
Anti-ATM (R3008H) Mouse Monoclonal Antibody, 100 µl (26140) Cancer Research NewEast Biosciences NEBA10172
Background Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activ..
Anti-ATM Rabbit Polyclonal Antibody, 100 µl (21276) Cancer Research NewEast Biosciences NEBA10090
Background Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activ..
Anti-B-RAF (G469E) Mouse Monoclonal Antibody, 100 µl (26196) Signal Transduction NewEast Biosciences NEBA10197
Background BRAF belongs to a family of serine-threonine protein kinases.BRAF belongs to a family of serine-threonine protein kinases As a part of a signaling pathway known as the the RAS/MAPK pathway, it plays an important part in many cellular processes. The processes include cell proliferation,..
Anti-B-Raf (N581S) Mouse Monoclonal Antibody, 100 µl (26109) Signal Transduction NewEast Biosciences NEBA10155
Background B-Raf is a member of the Raf family of Ser/Thr protein kinases. It functions downstream of Ras to regulate the MAP kinase signaling pathway. Mutations in the BRAF gene cause diseases. Inherited mutations in BRAF cause cardiofaciocutaneous syndrome. Acquired mutations in BRAF have been ..
Anti-B-Raf (V600D) Mouse Monoclonal Antibody, 100 µl (26184) Signal Transduction NewEast Biosciences NEBA10191
Background B-Raf is a member of the Raf family of Ser/Thr protein kinases. It functions downstream of Ras to regulate the MAP kinase signaling pathway. Mutations in the BRAF gene cause diseases. Inherited mutations in BRAF cause cardiofaciocutaneous syndrome. Acquired mutations in BRAF have been ..
Anti-B-Raf (V600E) Mouse Monoclonal Antibody, 100 µl (26039) Signal Transduction NewEast Biosciences NEBA10126
Background B-Raf is a member of the Raf family of Ser/Thr protein kinases. It functions downstream of Ras to regulate the MAP kinase signaling pathway. Mutations in the BRAF gene cause diseases. Inherited mutations in BRAF cause cardiofaciocutaneous syndrome. Acquired mutations in BRAF have been ..
Anti-B-Raf (V600K) Mouse Monoclonal Antibody, 100 µl (26110) Signal Transduction NewEast Biosciences NEBA10156
Background B-Raf is a member of the Raf family of Ser/Thr protein kinases. It functions downstream of Ras to regulate the MAP kinase signaling pathway. Mutations in the BRAF gene cause diseases. Inherited mutations in BRAF cause cardiofaciocutaneous syndrome. Acquired mutations in BRAF have been ..
Anti-B-Raf (V600R) Mouse Monoclonal Antibody, 100 µl (26182) Signal Transduction NewEast Biosciences NEBA10190
Background B-Raf is a member of the Raf family of Ser/Thr protein kinases. It functions downstream of Ras to regulate the MAP kinase signaling pathway. Mutations in the BRAF gene cause diseases. Inherited mutations in BRAF cause cardiofaciocutaneous syndrome. Acquired mutations in BRAF have been ..
Anti-B-Raf Mouse Monoclonal Antibody, 100 µl (26129) Signal Transduction NewEast Biosciences NEBA10165
Background B-Raf is a member of the Raf family of Ser/Thr protein kinases. It functions downstream of Ras to regulate the MAP kinase signaling pathway. Mutations in the BRAF gene cause diseases. Inherited mutations in BRAF cause cardiofaciocutaneous syndrome. Acquired mutations in BRAF have been ..
Anti-B-Raf Rabbit Polyclonal Antibody, 100 µl (21271) Signal Transduction NewEast Biosciences NEBA10087
Background B-Raf is a member of the Raf family of Ser/Thr protein kinases. It functions downstream of Ras to regulate the MAP kinase signaling pathway. Mutations in the B-RAF gene cause diseases. Inherited mutations in B-RAF cause cardiofaciocutaneous syndrome. Acquired mutations in B-RAF have be..
Anti-Bag1 Mouse Monoclonal Antibody, 100 µl (26135) Cancer Research NewEast Biosciences NEBA10168
Background BAG family molecular chaperone regulator 1 is a protein that is encoded by the BAG1 gene. It binds to oncogene BCL2, by which enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. BAG gene has been implicated in a..
Anti-Bag1 Rabbit Polyclonal Antibody, internal immunogen, 100 µl (21231) Cancer Research NewEast Biosciences NEBA10083
Background BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene. It binds to oncogene BCL2, by which enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. BAG gene has been impli..
Anti-Bag1 Rabbit Polyclonal Antibody, N-terminal immunogen, 100 µl (21230) Cancer Research NewEast Biosciences NEBA10082
Background BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene. It binds to oncogene BCL2, by which enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. BAG gene has been impli..
Anti-BCL-2 Rabbit Polyclonal Antibody, 100 µl (21224) Cancer Research NewEast Biosciences NEBA10081
Background BCL-2 (B-Cell Lymphoma 2) is the founding member of the Bcl-2 family of apoptosis regulator proteins. There are two isoforms of BCL-2: Isoform 1, also known as 1G5M, and Isoform 2, also known as 1G5O/1GJH. The BCL-2 gene has been implicated in a number of cancers, including melanoma, bre..
Anti-BMP3 Mouse Monoclonal Antibody, 100 µl (26051) Cell Biology NewEast Biosciences NEBA10131
Background BMP3 belongs to the TGF-beta family. It negatively regulates bone density and antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentiation and ossification. BMP3 is secreted and highly expressed in fracture tissue, particularly in osteoblasts, osteoclasts ..
Anti-c-myc Epitope Tag Mouse Monoclonal Antibody (DBOA10004), 100 ug Signal Transduction DBio DBOA10004
Anti-c-myc Epitope Tag (EQKLISEEDL) Mouse Monoclonal Antibody (DBOA10004), 100 ug Background: A myc tag EQKLISEEDL is a peptide tag derived from the c-myc gene product that can be added to a protein using recombinant DNA technology. It can be used for affinity chromatography, then used to..
Anti-cAMP Mouse Monoclonal Antibody, 30 µl (26002-1) Signal Transduction NewEast Biosciences NEBA10098
Background cAMP is a ubiquitous second messenger mediating cellular responses to various exogenous and endogenous signaling molecules. cAMP regulates physiological processes by activating protein kinases, gating specific ion channels, modulating cellular cyclic nucleotide concentrations through pho..
Anti-Cdc42 Chicken Polyclonal Antibody, 100 µl (21019) Signal Transduction NewEast Biosciences NEBA10015
Background Small GTPases are a superfamily of cellular signaling regulators. Cdc42 belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Cdc42, and the hydrolysis of GTP to GDP renders it inactive. GTP hydr..
Anti-Cdc42 Mouse Monoclonal Antibody, 100 µl (26008) Signal Transduction NewEast Biosciences NEBA10104
Background Small GTPases are a superfamily of cellular signaling regulators. Cdc42 belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Cdc42, and the hydrolysis of GTP to GDP renders it inactive. GTP hydr..
Anti-Cdc42 Rabbit Polyclonal Antibody, 100 µl (21010) Signal Transduction NewEast Biosciences NEBA10007
Background Small GTPases are a superfamily of cellular signaling regulators. Cdc42 belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Cdc42, and the hydrolysis of GTP to GDP renders it inactive. GTP hydr..
Anti-Cdc42+Rac1+RhoA Rabbit Polyclonal Antibody, 100 µl (21035) Signal Transduction NewEast Biosciences NEBA10023
Background Small GTPases are a superfamily of cellular signaling regulators. The Rho sub-family GTPases regulate cell motility, cell division, and gene transcription. Tested Applications ELISA, WB, IHC Source Species Rabbit Species Reactivity Rho family pan antibody recognizes Cdc42, Rac1, an..
Anti-cGMP Mouse Monoclonal Antibody, 30 µl (26001-1) Signal Transduction NewEast Biosciences NEBA10097
Background cGMP is a ubiquitous second messenger mediating cellular responses to various exogenous and endogenous signaling molecules. cGMP regulates physiological processes by activating protein kinases, gating specific ion channels, and modulating cellular cyclic nucleotide concentrations through..
Anti-Clusterin Mouse Monoclonal Antibody, 100 µl (26088) Cancer Research NewEast Biosciences NEBA10151
Background Clusterin (apolipoprotein J) belongs to the clusterin family, is a 75 - 80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. It is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. Cluste..
Anti-Clusterin Mouse Monoclonal Antibody, N-terminal immunogen, 100 µl (26043) Cancer Research NewEast Biosciences NEBA10127
Background Clusterin (apolipoprotein J) belongs to the clusterin family, is a 75 - 80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. It is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. Cluste..
Anti-CTNNB1 (S37F) Mouse Monoclonal Antibody, 100 µl (26168) Signal Transduction NewEast Biosciences NEBA10185
Background CTNNB1 protein is a dual function protein. It is a subunit of a complex of proteins that from adherens junctions, which are important for the establishment and maintenance of epithelial cell layers by regulating cell growth and adhesion between adjacent cells. CTNNB1 protein also pulls d..
Anti-CTNNB1 (S37Y) Mouse Monoclonal Antibody, 100 µl (26296) Signal Transduction NewEast Biosciences NEBA10205
Background CTNNB1 protein is a dual function protein. It is a subunit of a complex of proteins that form adherens junctions, which are important for the establishment and maintenance of epithelial cell layers by regulating cell growth and adhesion between adjacent cells. CTNNB1 protein also pulls d..
Anti-CTNNB1 (T41A) Mouse Monoclonal Antibody, 100 µl (26305) Signal Transduction NewEast Biosciences NEBA10206
Background CTNNB1 protein is a dual function protein. It is a subunit of a complex of proteins that from adherens junctions, which are important for the establishment and maintenance of epithelial cell layers by regulating cell growth and adhesion between adjacent cells. CTNNB1 protein also pulls d..
Anti-Cyclin B1 Rabbit Polyclonal Antibody, 100 µl (21210) Cancer Research NewEast Biosciences NEBA10078
Background Cyclin B1 is a regulatory protein belongs to the cyclin family and involved in mitosis. Upon activation, cyclin B1 form a complex with Cdk1. Cyclin B1-Cdk1 complex is involved in the early events of mitosis such as chromosome condensation, nuclear envelope breakdown, and spindle pole ass..
Anti-Cystatin C Mouse Monoclonal Antibody, 100 µl (26085) Neuroscience NewEast Biosciences NEBA10150
Background Cystatin C, belongs to the cystatin family, is an inhibitor of cysteine proteinases, and is thought to serve an important physiological role as a local regulator of this enzyme activity. It is secreted. Cystatin C is expressed in the highest levels in the epididymis, vas deferens, brain,..
Anti-Cystatin C Mouse Monoclonal Antibody, C-terminal immunogen, 100 µl (26044) Neuroscience NewEast Biosciences NEBA10128
Background Cystatin C is mainly used as a biomarker of kidney function. It is a potent inhibitor of cysteine proteases. Tested Applications ELISA, WB, IHC, IP Source Species Mouse Species Reactivity Cystatin C antibody recognizes Cystatin C proteins of vertebrates. Datasheet   Wes..
Anti-Cystatin C Rabbit Polyclonal Antibody, 100 µl (21108) Neuroscience NewEast Biosciences NEBA10055
Background Cystatin C, belongs to the cystatin family, is an inhibitor of cysteine proteinases, and is thought to serve an important physiological role as a local regulator of this enzyme activity. It is secreted. Cystatin C is expressed in the highest levels in the epididymis, vas deferens, brain,..
Anti-EGFR (A839T) Mouse Monoclonal Antibody, 100 µl (26117) Signal Transduction NewEast Biosciences NEBA10159
Background EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLC..
Anti-EGFR (D761Y) Mouse Monoclonal Antibody, 100 µl (26120) Signal Transduction NewEast Biosciences NEBA10161
Background EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLC..
Anti-EGFR (G719A) Mouse Monoclonal Antibody, 100 µl (26115) Signal Transduction NewEast Biosciences NEBA10157
Background EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLC..
Anti-EGFR (G719S) Mouse Monoclonal Antibody, 100 µl (26083) Signal Transduction NewEast Biosciences NEBA10148
Background EGFR is a receptor tyrosine kinase for ligands of the EGF family. EGFR activates several signaling cascades to convert extracellular cues into appropriate cellular responses. Defects in EGFR are associated with cancers such as lung cancer. Tested Applications ELISA, WB, IF, IHC Source..
Anti-EGFR (G863D) Mouse Monoclonal Antibody, 100 µl (26119) Signal Transduction NewEast Biosciences NEBA10160
Background EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLC..
Anti-EGFR (L858Q) Mouse Monoclonal Antibody, 100 µl (26221) Signal Transduction NewEast Biosciences NEBA10198
Background EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLC..
Anti-EGFR (L858R) Mouse Monoclonal Antibody, 100 µl (26082) Signal Transduction NewEast Biosciences NEBA10147
Background EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLC..
Anti-EGFR (L861Q) Mouse Monoclonal Antibody, 100 µl (26077) Signal Transduction NewEast Biosciences NEBA10144
Background EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLC..
Anti-EGFR (N826S) Mouse Monoclonal Antibody, 100 µl (26116) Signal Transduction NewEast Biosciences NEBA10158
Background EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLC..
Anti-EGFR (V769L) Mouse Monoclonal Antibody, 100 µl (26121) Signal Transduction NewEast Biosciences NEBA10162
Background EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLC..
Anti-EGFR (vIII) Mouse Monoclonal Antibody, 100 µl (26176) Signal Transduction NewEast Biosciences NEBA10189
Background EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLC..
Anti-EGFR Rabbit Polyclonal Antibody, 100 µl (21272) Signal Transduction NewEast Biosciences NEBA10088
Background EGFR is a receptor tyrosine kinase for ligands of the EGF family. EGFR activates several signaling cascades to convert extracellular cues into appropriate cellular responses. Defects in EGFR are associated with cancers such as lung cancer. Tested Applications ELISA, WB, IHC Source Spe..
Anti-EML4-ALK Mouse Monoclonal Antibody, 100 µl (26242) Signal Transduction NewEast Biosciences NEBA10201
Background EML4-ALK is a fusion-type protein kinase that can be found in many tumors, such as anaplastic large cell lymphoma, inflammatory myofibroblastic tumor, neuroblastoma and NSCLC, and so on. It is generated as a result of a small inversion within the short arm of human chromosome 2. EML4-ALK..
Anti-ER1 Rabbit Polyclonal Antibody, 100 µl (21220) Signal Transduction NewEast Biosciences NEBA10080
Background Estrogen receptor (ER) is a member of the nuclear hormone family of intracellular receptors. There are two different forms of the estrogen receptor, usually referred to as α and β, each encoded by a separate genes (ESR1 and ESR2, respectively). Upon activation by estrogen, the estrogen r..
Anti-ErbB2 (V777A) mouse monoclonal Antibody, 100 µl (26080) Signal Transduction NewEast Biosciences NEBA10145
Background The ErbB family is composed of four plasma membrane-bound receptor tyrosine kinases. Amplification or over-expression of the ERBB2 gene occurs in approximately 30% of breast cancers. HER2 is encoded by ERBB2, a known proto-oncogene located at the long arm of human chromosome 17(17q21-q22..
Anti-ERBB2 Mouse Monoclonal Antibody, 100 µl (26127) Signal Transduction NewEast Biosciences NEBA10163
Background The HER-2/neu oncogene, a member of the epidermal growth factor receptor or erb-B gene-like family, encodes a transmembrane tyrosine kinase receptor that mediates extracellular signals activated by epidermal growth factors. Her2 abnormal has been strongly associated with many malignant t..
Anti-ERBB2 Rabbit polyclonal Antibody, C-terminal immunogen, 100 µl (21200) Signal Transduction NewEast Biosciences NEBA10074
Background The HER-2/neu oncogene, a member of the epidermal growth factor receptor or erb-B gene-like family, encodes a transmembrane tyrosine kinase receptor that mediates extracellular signals activated by epidermal growth factors. Her2 abnormal has been strongly associated with many malignant t..
Anti-ErbB2 Rabbit Polyclonal Antibody, internal immunogen, 100 µl (21202) Signal Transduction NewEast Biosciences NEBA10075
Background The ErbB family is composed of four plasma membrane-bound receptor tyrosine kinases. Amplification or over-expression of the ERBB2 gene occurs in approximately 30% of breast cancers. HER2 is encoded by ERBB2, a known proto-oncogene located at the long arm of human chromosome 17(17q21-q22..
Anti-EYA2 Mouse Monoclonal Antibody, 100 µl (26096) Cancer Research NewEast Biosciences NEBA10154
Background EYA2 may be involved in development of the eye. It promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. ..
Anti-EYA2 Mouse Monoclonal Antibody, N-terminal immunogen, 100 µl (26052) Cancer Research NewEast Biosciences NEBA10132
Background EYA2 may be involved in development of the eye. It promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. ..
Anti-EYA2 Rabbit Polyclonal Antibody, 100 µl (21128) Cancer Research NewEast Biosciences NEBA10063
Background EYA2 (eyes absent homolog 2) functions as a tyrosine phosphatase that specifically dephosphorylates Tyr-142 of histone H2AX. EYA2 promotes efficient DNA repair and coactivates SIX1. Together with SIX1 and DACH2, EYA2 seems to be involved in myogenesis. Tested Applications ELISA, WB, IH..
Anti-Fascin Mouse Monoclonal Antibody, internal immunogen, 100 µl (26013) Cell Biology NewEast Biosciences NEBA10108
Background Fascin is an ~58 kDa monomeric actin filament bundling protein. It is required to maximally cross-link the actin filaments into straight, compact, and rigid bundles, and contributes to the formation of filopodia that are critical for cell migration. Elevated levels of fascin have been fo..
Anti-Fascin Mouse Monoclonal Antibody, N-terminal immunogen, 100 µl (26012) Cell Biology NewEast Biosciences NEBA10107
Background Fascin is an ~58 kDa monomeric actin filament bundling protein. It is required to maximally cross-link the actin filaments into straight, compact, and rigid bundles, and contributes to the formation of filopodia that are critical for cell migration. Elevated levels of fascin have been fo..
Anti-FGF2 Mouse Monoclonal Antibody [F2G] (DBOA10001), 100 ug Signal Transduction DBio DBOA10001
This is a mouse monoclonal IgM antibody against humna Fibroblast Growth Factor-2. Background FGF2, also known as Basic fibroblast growth factor, bFGF, or FGF-β is a member of the fibroblast growth factor family [1]. In normal tissue, basic fibroblast growth factor is present in basement..
Anti-FLAG Epitope Tag Mouse Monoclonal Antibody (DBOA10007) Techniques DBio DBOA10007
Anti-FLAG Epitope Tag Mouse Monoclonal Antibody (DBOA10007), 100 ug The antibody recognizes the FLAG epitope in FLAG-tagged fusion proteins at the N-terminus or C-terminus. Background A fusion tag called FLAG and consisting of eight amino acids Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys including an e..
Protein, Expression, Analysis, Techniques
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