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Anti-Kim-1 Rabbit Polyclonal Antibody, 100 µl (21110) Immunology NewEast Biosciences NEBA10056
Background Kidney injury molecule-1 (Kim-1) is a type 1 membrane protein with extracellular immunoglobulin and mucin domains. Kim-1 mRNA and protein are expressed at very low levels in normal kidney, but expression increases dramatically after injury in proximal tubule epithelial cells in postische..
Anti-MEK1 (I111S) Mouse Monoclonal Antibody, 100 µl (26264) Signal Transduction NewEast Biosciences NEBA10203
Background MEK1 (also known as extracellular signal-regulated kinases, ERKs) plays important role in the MAP kinase cascade, which transduces multiple extracellular signals to control cell growth, proliferation and differentiation. Activated upon growth factors stimulation, MEK1 phosphorylates MAPK..
Anti-MEK1 (N382H) Mouse Monoclonal Antibody, 100 µl (26270) Signal Transduction NewEast Biosciences NEBA10204
Background MEK1 (also known as extracellular signal-regulated kinases, ERKs) plays important role in the MAP kinase cascade, which transduces multiple extracellular signals to control cell growth, proliferation and differentiation. Activated upon growth factors stimulation, MEK1 phosphorylates MAPK..
Anti-MEK1 (Q56P) Mouse Monoclonal Antibody, 100 µl (26222) Signal Transduction NewEast Biosciences NEBA10199
Background MEK1 (also known as extracellular signal-regulated kinases, ERKs) plays important role in the MAP kinase cascade, which transduces multiple extracellular signals to control cell growth, proliferation and differentiation. Activated upon growth factors stimulation, MEK1 phosphorylates MAPK..
Anti-MUC1 Rabbit Polyclonal Antibody, 100 µl (21123) Cancer Research NewEast Biosciences NEBA10061
Background Mucin-1 proteins line the apical surface of highly polarized epithelial cells in the lungs, stomach, intestines, and eyes. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain. Overexpression of MUC1 is often associated with colon, br..
Anti-Orai1 Rabbit Polyclonal Antibody  (Orai1-L1), 100 µl (21001) Signal Transduction NewEast Biosciences NEBA10001
Background Store-operated calcium channels (SOCs) play essential functions in various physiological processes. Orai1 (also named CRACM1) is a critical molecular component of SOCs. Orai1 protein is a ~35kDa plasma membrane protein with 4 transmembrane domains. Human patients with a severe combined i..
Anti-Orai1 Rabbit Polyclonal Antibody  (Orai1-L2), 100 µl (21002) Signal Transduction NewEast Biosciences NEBA10002
Background Store-operated calcium channels (SOCs) play essential functions in various physiological processes. Orai1 (also named CRACM1) is a critical molecular component of SOCs. Orai1 protein is a ~35kDa plasma membrane protein with 4 transmembrane domains. Human patients with a severe combined i..
Anti-PIK3CA (D549N) Mouse Monoclonal Antibody, 100 µl (26215) Signal Transduction NewEast Biosciences NEBA10233
Background Phosphatidyl 3-kinases (PI3K) are a family of lipid kinases involved in many cellular processes, including cell growth, proliferation, differentiation, motility, and survival. It is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. Mutants of PIK3CA has been found..
Anti-PIK3CA (E542Q) Mouse Monoclonal Antibody, 100 µl (26210) Signal Transduction NewEast Biosciences NEBA10232
Background Phosphatidyl 3-kinases (PI3K) are a family of lipid kinases involved in many cellular processes, including cell growth, proliferation, differentiation, motility, and survival. It is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. Mutants of PIK3CA has been found..
Anti-PIK3CA (E545K) Rabbit Polyclonal Antibody, 100 µl (21145) Signal Transduction NewEast Biosciences NEBA10064
Background Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The catalytic subunit is encoded by the PIK3CA gene . It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 . The PIK3CA gene is one of the most frequently mutated genes in hum..
Anti-PIK3CA (H1047R) Rabbit Polyclonal Antibody, 100 µl (21146) Signal Transduction NewEast Biosciences NEBA10065
Background Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The catalytic subunit is encoded by the PIK3CA gene. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2. The PIK3CA gene is one of the most frequently mutated genes in human cance..
Anti-PIK3CA (H1047Y) Mouse Monoclonal Antibody, 100 µl (26216) Signal Transduction NewEast Biosciences NEBA10234
Background Phosphatidyl 3-kinases (PI3K) are a family of lipid kinases involved in many cellular processes, including cell growth, proliferation, differentiation, motility, and survival. It is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. Mutants of PIK3CA has been found..
Anti-PIK3CA (Q546K) Mouse Monoclonal Antibody, 100 µl (26138) Signal Transduction NewEast Biosciences NEBA10171
Background Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform. Phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. Belongs to the PI3/PI4-kinase family. Located to cytosol, lamellipodium and phosphatidylinositol 3-kinase complex. Teste..
Anti-PIK3CA Mouse Monoclonal Antibody, 100 µl (26069) Signal Transduction NewEast Biosciences NEBA10139
Background Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The catalytic subunit is encoded by the PIK3CA gene. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2. The PIK3CA gene is one of the most frequently mutated genes in human cance..
Anti-PTEN Mouse Monoclonal Antibody, 100 µl (26171) Cancer Research NewEast Biosciences NEBA10188
Background Phosphatase and tensin homolog (PTEN) was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. It is one of the most commonly lost tumor suppressors in human cancer. During tumor development, mutations and deletions of PTEN occur that inactivat..
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